Grade Post Therapy Clin (yc) (Cervix Sarcoma)

Note 1 Leave post therapy grade blank when

• No neoadjuvant therapy

• Clinical or pathological case only

• Neoadjuvant therapy completed, no microscopic exam is done prior to surgery/resection of primary tumor

• There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological

Note 2 Assign the highest grade from the microscopically sampled specimen of the primary site following neoadjuvant therapy or primary systemic/radiation therapy.

• Per clarification from the CAP Cancer Committee based on the CAP Protocol, the following histologies must be assigned a G3 (code 3) Serous, clear cell, undifferentiated/de-differentiated carcinomas, carcinosarcomas, and mixed mesodermal tumors (Mullerian/MMMT) are high risk (high grade)

Note 3 For endometrioid carcinomas only

• If “low grade” is documented, code 2 (FIGO Grade 2)

• If “high grade” is documented, code 3 (FIGO Grade 3)Note 3 If there are multiple tumors with different grades abstracted as one primary, code the highest grade.

Note 4 If there are multiple tumors with different grades abstracted as one primary, code the highest grade.

Note 5 G3 includes anaplastic.

Note 6 Code 9 (unknown) when

• Microscopic exam is done after neoadjuvant therapy and grade from the primary site is not documented

• Microscopic exam is done after neoadjuvant therapy and there is no residual cancer

• Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available